Moïse Coëffier Selected Research

Ubiquitinated Proteins

1/2019	Colonic Proteome Signature in Immunoproteasome-Deficient Stressed Mice and Its Relevance for Irritable Bowel Syndrome.
7/2015	Glutamine enema regulates colonic ubiquitinated proteins but not proteasome activities during TNBS-induced colitis leading to increased mitochondrial activity.
9/2014	Hyperhomocysteinemia-induced oxidative stress differentially alters proteasome composition and activities in heart and aorta.
11/2013	Evaluation of ubiquitinated proteins by proteomics reveals the role of the ubiquitin proteasome system in the regulation of Grp75 and Grp78 chaperone proteins during intestinal inflammation.

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Moïse Coëffier Research Topics

Disease

14	Inflammation (Inflammations) 01/2018 - 04/2002
12	Anorexia 01/2021 - 12/2010
10	Irritable Bowel Syndrome (Syndrome, Irritable Bowel) 12/2020 - 05/2010
9	Colitis 01/2019 - 10/2010
9	Mucositis 01/2016 - 02/2008
6	Anorexia Nervosa 01/2022 - 06/2015
6	Body Weight (Weight, Body) 01/2021 - 04/2008
6	Diarrhea 01/2019 - 06/2005
5	Feeding and Eating Disorders (Eating Disorder) 01/2020 - 04/2008
4	Obesity 01/2020 - 08/2015
4	Insulin Resistance 01/2019 - 02/2005
4	Crohn Disease (Crohn's Disease) 03/2017 - 12/2008
4	Neoplasms (Cancer) 01/2016 - 01/2009
4	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 11/2013 - 07/2006
3	Dysbiosis 01/2021 - 06/2012
3	Hypersensitivity (Allergy) 12/2020 - 12/2011
3	Necrosis 01/2020 - 01/2009
3	Hyperglycemia 01/2019 - 03/2006
3	Malnutrition (Nutritional Deficiencies) 01/2018 - 04/2007
3	Atrophy 01/2017 - 02/2008
3	Critical Illness (Critically Ill) 01/2010 - 02/2005
2	Starvation 11/2019 - 06/2015
2	Weight Loss (Weight Reduction) 01/2018 - 01/2016
2	Shock 08/2013 - 05/2007
2	Abdominal Pain (Pain, Abdominal) 08/2013 - 12/2011
1	COVID-19 01/2021
1	Bulimia (Binge Eating) 01/2020
1	Binge-Eating Disorder (Binge Eating Disorder) 12/2019
1	Bulimia Nervosa 12/2019
1	Mood Disorders (Mood Disorder) 06/2019
1	Wounds and Injuries (Trauma) 01/2017
1	Cachexia 01/2016
1	Insulinoma 08/2015
1	Type 2 Diabetes Mellitus (MODY) 08/2015
1	Fibrosis (Cirrhosis) 12/2014

Drug/Important Bio-Agent (IBA)

16	Glutamine (L-Glutamine)FDA Link 06/2019 - 04/2002
15	Proteins (Proteins, Gene)FDA Link 11/2019 - 06/2006
8	Sulfonic AcidsIBA 01/2019 - 10/2010
8	Methotrexate (Mexate)FDA LinkGeneric 01/2016 - 01/2009
5	Peptides (Polypeptides)IBA 01/2022 - 04/2008
5	Immunoglobulin G (IgG)IBA 12/2019 - 01/2012
5	ProteomeIBA 11/2019 - 03/2010
5	Glucose (Dextrose)FDA LinkGeneric 01/2019 - 02/2005
5	Proteasome Endopeptidase Complex (Proteasome)IBA 07/2015 - 05/2010
5	CytokinesIBA 04/2012 - 04/2002
4	NeuropeptidesIBA 01/2021 - 04/2008
4	Ubiquitinated ProteinsIBA 01/2019 - 11/2013
4	GhrelinIBA 01/2016 - 01/2013
4	OccludinIBA 08/2013 - 05/2010
3	Messenger RNA (mRNA)IBA 01/2021 - 10/2010
3	Biological ProductsIBA 01/2021 - 09/2008
3	Insulin (Novolin)FDA Link 01/2019 - 03/2006
3	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 01/2018 - 07/2012
3	Tight Junction ProteinsIBA 01/2017 - 12/2011
3	UbiquitinIBA 07/2015 - 11/2013
3	AutoantibodiesIBA 01/2012 - 04/2008
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 10/2010 - 07/2006
2	Immunoglobulins (Immunoglobulin)IBA 01/2022 - 01/2016
2	Appetite Depressants (Anorectics)IBA 01/2021 - 01/2020
2	FructoseIBA 12/2020 - 03/2017
2	Melanocyte-Stimulating Hormones (MSH)IBA 12/2019 - 01/2012
2	EnzymesIBA 03/2017 - 07/2012
2	Claudin-1IBA 11/2016 - 04/2012
2	Arginine (L-Arginine)FDA Link 08/2014 - 01/2010
2	Phenobarbital (Luminal)FDA Link 08/2013 - 03/2010
2	alpha-Linolenic Acid (Linolenic Acid)IBA 07/2012 - 10/2010
2	Fish OilsIBA 07/2012 - 10/2011
2	Vascular Cell Adhesion Molecule-1 (Vascular Cell Adhesion Molecule 1)IBA 07/2012 - 10/2011
2	Whey ProteinsIBA 08/2010 - 04/2010
2	Caseins (Casein)FDA Link 08/2010 - 04/2010
2	Transforming Growth Factor beta (TGF-beta)IBA 08/2010 - 04/2010
2	Amino Acids FDA Link 03/2010 - 01/2009
2	MelanocortinsIBA 09/2008 - 04/2008
1	Neuropeptide YIBA 01/2021
1	Biological FactorsIBA 01/2021
1	Pro-Opiomelanocortin (Proopiomelanocortin)IBA 01/2021
1	Biomarkers (Surrogate Marker)IBA 01/2020
1	Type 4 Melanocortin Receptor (Melanocortin-4 Receptor)IBA 12/2019
1	EpitopesIBA 12/2019
1	Adenosine Triphosphate (ATP)IBA 11/2019
1	Branched-Chain Amino AcidsIBA 06/2019
1	IncretinsIBA 01/2019
1	NF-kappa B (NF-kB)IBA 01/2019
1	Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA 01/2018
1	Fatty Acids (Saturated Fatty Acids)IBA 01/2018
1	ImmunosorbentsIBA 03/2017
1	Antineutrophil Cytoplasmic Antibodies (ANCA)IBA 03/2017
1	AntibodiesIBA 03/2017
1	Leukocyte L1 Antigen Complex (Calgranulin)IBA 03/2017
1	MicronutrientsIBA 01/2017
1	Hormones (Hormone)IBA 01/2016
1	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 12/2014

Therapy/Procedure

7	Drug Therapy (Chemotherapy) 01/2016 - 02/2008
2	Intraperitoneal Injections 09/2014 - 01/2012
2	Therapeutics 07/2012 - 02/2008
2	Injections 01/2012 - 08/2010
2	Nutritional Support (Artificial Feeding) 03/2010 - 06/2005
1	Length of Stay 01/2021
1	Gastrectomy 01/2020
1	Enema (Enemas) 07/2015